Article
Superantigen-like effects and incidence of diabetes in NOD mice.
Diabetes - 1 Jul 1993
McDuffie M, Ostrowska A
Abstract excerpt
The population of T-cells that develops in any individual can be divided into families based on sequence differences in the beta-chain variable region of the T-cell receptor heterodimer. Major histocompatibility complex products and endogenous retroviral gene products have both been shown to exert powerful influences on the frequency distribution of T-cell receptor beta-chain variable region families in the...
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