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Article

TCR transgenic mice reveal the impact of type 1 diabetes loci on early and late disease checkpoints.

Immunology and cell biology - 1 Aug 2016

Hillhouse Erin E, Liston Adrian, Collin Roxanne, Desautels Eric, Goodnow Christopher C, Lesage Sylvie

Abstract excerpt

Linkage analysis studies for autoimmune diabetes have revealed multiple non-major histocompatibility complex (MHC) chromosomal regions linked to disease susceptibility. To date, more than 20 insulin-dependent diabetes (Idd) loci linked to diabetes susceptibility have been identified in NOD mice and validated via congenic breeding. Importantly, evidence suggests that Idd loci may regulate at least two pathological...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 27046082
DOI: 10.1038/icb.2016.27

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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