Genetic evidence for similar negative regulatory domains in the yeast transcription activators GAL4 and LAC9.

doi:10.1093/nar/18.17.5213

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Article

Genetic evidence for similar negative regulatory domains in the yeast transcription activators GAL4 and LAC9.

Nucleic acids research - 11 Sept 1990

Dickson R C, Gerardot C J, Martin A K

Abstract excerpt

The GAL4 protein of Saccharomyces cerevisiae and the LAC9 protein of Kluyveromyces lactis are transcription activator proteins with similar structure and function. Greatest similarity occurs in the C region near the carboxy terminus, where 16 of 18 amino acids are identical. The function of the C...

Topics

Amino Acid Sequence
DNA-Binding Proteins
Fungal Proteins
Gene Expression Regulation, Fungal
Kluyveromyces
Molecular Sequence Data
Operon
Phenotype
Repressor Proteins
Saccharomyces cerevisiae
Saccharomyces cerevisiae Proteins
Saccharomycetales
Sequence Homology, Nucleic Acid
Transcription Factors

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Identifiers

PMID: 2205838
DOI: 10.1093/nar/18.17.5213
PMCID: PMC332144

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 30 Aug 2026. Prepared record publication-2205838-2026-08-30.1. Manifest publication-graph-cohort-2026-08-30.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 30 Aug 2026.

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