Article
Role of eukaryotic-type functional domains found in the prokaryotic enhancer receptor factor sigma 54.
Cell - 7 Sept 1990
Sasse-Dwight S, Gralla J D
Abstract excerpt
E. coli sigma 54 protein confers on promoters containing its recognition sequence the ability to be activated from distant DNA sites. Its functional domains include two leucine zipper motifs, an acidic region, and a glutamine-rich domain. Several domains were disrupted and the assembly of mutant transcription complexes was probed in vivo by footprinting. Promoter recognition was seen to depend on a C-terminal...
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