Article
Sequence conservation in the Saccharomyces and Kluveromyces GAL11 transcription activators suggests functional domains.
Nucleic acids research - 11 Oct 1991
Mylin L M, Gerardot C J, Hopper J E, Dickson R C
Abstract excerpt
Efficient transcription of many Saccharomyces cerevisiae genes requires the GAL11 Protein. GAL11 belongs to a class of transcription activator that lacks a DNA-binding domain. Such proteins are thought to activate specific genes by complexing with DNA-bound proteins. To begin to understand the domain structure-function relationships of GAL11 we cloned and sequenced a homologue from the yeast Kluyveromyces lactis,...
Topics
- Amino Acid Sequence
- Base Sequence
- Blotting, Western
- Cloning, Molecular
- Fungal Proteins
- Galactose
- Gene Expression Regulation, Fungal
- Genetic Complementation Test
- Kluyveromyces
- Lactose
- Mediator Complex