Article
Epstein-Barr virus contributes to the malignant phenotype and to apoptosis resistance in Burkitt's lymphoma cell line Akata.
Journal of virology - 1 Nov 1998
Komano J, Sugiura M, Takada K
Abstract excerpt
In the present study, we established an in vitro system representing the Burkitt's lymphoma (BL)-type Epstein-Barr virus (EBV) infection which is characterized by expression of EBV-determined nuclear antigen 1 (EBNA-1) and absence of EBNA-2 and latent membrane protein 1 (LMP1) expression. EBV-neg...
Topics
- Animals
- Apoptosis
- Base Sequence
- Burkitt Lymphoma
- DNA Primers
- Epstein-Barr Virus Nuclear Antigens
- Gene Expression
- Genes, Viral
- Herpesvirus 4, Human
- Humans
- Mice
- Phenotype
- Proto-Oncogene Proteins c-bcl-2
- Transfection
- Tumor Cells, Cultured
- Viral Matrix Proteins