Article
Growth suppression of normal mammary epithelial cells by wild-type p53.
Oncogene - 1 Feb 1994
Merlo G R, Venesio T, Taverna D, Marte B M, Callahan R, Hynes N E
Abstract excerpt
p53 mutations are frequent in human breast cancer. In order to understand the role of p53 in the context of the accumulation of mutations in breast cancer, a model of non transformed mammary cells was sought. The HC11 cells are immortalized, non transformed rodent mammary epithelial cells which s...
Topics
- Alleles
- Animals
- Base Sequence
- Blotting, Southern
- Cell Division
- Cell Line
- DNA
- Epithelial Cells
- Epithelium
- Exons
- Female
- Gene Deletion
- Genes, p53
- Mammary Glands, Animal
- Molecular Sequence Data
- Mutation
- Polymerase Chain Reaction
- Precipitin Tests