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Article

Insights into apoptosis mechanisms induced by DNA-damaging agents in Burkitt's lymphoma cells.

Cancer investigation - 1 Oct 2009

Simões Magluta Eliane Pereira, Vasconcelos Flavia da Cunha, Maia Raquel Ciuvalschi, Klumb Claudete Esteves

Abstract excerpt

p53 protein induces cell cycle arrest, DNA repair, or apoptosis of damaged cells. Loss of wild-type p53 (wt-p53) function was shown to be associated with upregulation of survivin and resistance to therapy. Here we investigated the effects of DNA-damage agents in inducing apoptosis and cell cycle arrest, and modulation of survivin levels in two Burkitt's lymphoma (BL) cell lines with different p53 mutations. Our...

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Source

Identifiers

PMID: 19557576
DOI: 10.1080/07357900902849624

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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