Consecutive inactivation of both alleles of the gb110 gene has no effect on the proliferation and differentiation of mouse embryonic stem cells.

doi:10.1016/0378-1119(93)90381-c

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Article

Consecutive inactivation of both alleles of the gb110 gene has no effect on the proliferation and differentiation of mouse embryonic stem cells.

Gene - 30 Apr 1993

Hamann L, Jensen K, Harbers K

Abstract excerpt

The gene gb110 was originally identified by provirus integration in the Mov10 mouse strain and encodes a 110-kDa protein with potential GTP-binding activity. The gene is evolutionarily conserved, and its expression is controlled in a developmentally and cell-cycle-specific manner, suggesting that...

Topics

Alleles
Animals
Blotting, Northern
Blotting, Southern
Cell Differentiation
Cell Division
Cell Line
GTP-Binding Proteins
Gene Expression
Genetic Vectors
Mice
Phenotype
Recombination, Genetic
Stem Cells

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