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Article

Chimeric c-Jun containing an heterologous homodimerization domain transforms primary chick embryo fibroblasts.

Oncogene - 1 May 1993

Castellazzi M, Loiseau L, Piu F, Sergeant A

Abstract excerpt

To investigate a possible role for c-Jun homodimers in c-Jun-mediated transformation, we designed two chimeric c-Jun derivatives, called c-Juneb1 and c-Jungcn4. In these chimeric derivatives the natural dimerization domain of c-Jun was replaced by the heterologous homodimerization domain of the Epstein-Barr virus EB1 or the yeast GCN4 transcription factor. Chick embryo fibroblasts chronically infected with...

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PMID: 8479740

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

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Chimeric c-Jun containing an heterologous homodimerization domain transforms primary chick embryo fibroblasts.PMID 8479740Read ↗

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