c-jun is essential for normal mouse development and hepatogenesis.

doi:10.1038/365179a0

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Article

c-jun is essential for normal mouse development and hepatogenesis.

Nature - 9 Sept 1993

Hilberg F, Aguzzi A, Howells N, Wagner E F

Abstract excerpt

The proto-oncogene c-jun is the cellular homologue of v-jun, the transforming oncogene of the avian sarcoma virus 17 (ref. 1). c-jun encodes one major component of the AP-1 transcription factor complex and is expressed in many organs during mouse development and in the adult. Because of its rapid...

Topics

Animals
Chimera
Clone Cells
Crosses, Genetic
Embryo, Mammalian
Embryonic and Fetal Development
Female
Fetal Death
Genes, jun
Genotype
Glucose-6-Phosphate Isomerase
Liver
Male
Mice
Mice, Inbred C57BL
Mice, Transgenic
Mutation
Proto-Oncogene Proteins c-jun

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