Article
Amplification and loss of repeat units of the human minisatellite MS1 integrated in chromosome III of a haploid yeast strain.
Molecular & general genetics : MGG - 1 Apr 1993
Cederberg H, Agurell E, Hedenskog M, Rannug U
Abstract excerpt
Minisatellites comprise arrays of tandemly repeated short DNA sequences which show extensive variation in repeat unit number. The mechanisms that underlie this length variation are not understood. In order to study processes influencing length changes of minisatellites, we integrated the human minisatellite MS1 into a haploid strain of the yeast Saccharomyces cerevisiae. Frequent spontaneous generation of MS1...
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