Mutations occurring at the human minisatellite MS1 integrated in haploid yeast are similar to MS1 mutations in humans.

doi:10.1007/s004380050388

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Article

Mutations occurring at the human minisatellite MS1 integrated in haploid yeast are similar to MS1 mutations in humans.

Molecular & general genetics : MGG - 18 Mar 1997

Maleki S, Cederberg H, Rannug U

Abstract excerpt

MS1 is one of the most variable minisatellites so far isolated from the human genome. We have previously reported an MS1 length-mutant frequency of 29.6% in overnight cultures of haploid yeast cells carrying a 1.35 kb MS1 allele. Here we present data on the instability of alleles with lengths ran...

Topics

Alleles
Base Sequence
DNA Replication
Escherichia coli
Humans
Minisatellite Repeats
Mutagenesis
Saccharomyces cerevisiae
Species Specificity

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