Article
Mutations occurring at the human minisatellite MS1 integrated in haploid yeast are similar to MS1 mutations in humans.
Molecular & general genetics : MGG - 18 Mar 1997
Maleki S, Cederberg H, Rannug U
Abstract excerpt
MS1 is one of the most variable minisatellites so far isolated from the human genome. We have previously reported an MS1 length-mutant frequency of 29.6% in overnight cultures of haploid yeast cells carrying a 1.35 kb MS1 allele. Here we present data on the instability of alleles with lengths ranging from 0.15 kb to 2.05 kb, which revealed a threshold of 0.75 kb, at and below which MS1 alleles were entirely...
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