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Article

Meiotic instability of human minisatellite CEB1 in yeast requires DNA double-strand breaks.

Nature genetics - 1 Nov 1999

Debrauwère H, Buard J, Tessier J, Aubert D, Vergnaud G, Nicolas A

Abstract excerpt

Minisatellites are tandemly repeated DNA sequences of 10-100-bp units. Some minisatellite loci are highly unstable in the human germ line, and structural analysis of mutant alleles has suggested that repeat instability results from a recombination-based process. To provide insights into the molecular mechanism of human minisatellite instability, we developed Saccharomyces cerevisiae strains carrying alleles of...

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PMID: 10545956
DOI: 10.1038/15557

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

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Meiotic instability of human minisatellite CEB1 in yeast requires DNA double-strand breaks.PMID 10545956Read ↗

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