Article
Mutations at the human minisatellite MS32 integrated in yeast occur with high frequency in meiosis and involve complex recombination events.
Molecular & general genetics : MGG - 1 Sept 1997
Appelgren H, Cederberg H, Rannug U
Abstract excerpt
Minisatellites are composed of tandem repetitive DNA sequences and are present at many positions in the human genome. They frequently mutate to new length alleles in the germline, by complex and incompletely understood recombination mechanisms which may operate during meiosis. In several minisatellites the mutation events are restricted to one end of the repeat array, indicating a possible association with...
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