Article
Cis-regulation of inter-allelic exchanges in mutation at human minisatellite MS205 in yeast.
Gene - 31 May 1999
He Q, Cederberg H, Armour J A, May C A, Rannug U
Abstract excerpt
Tandemly repeated DNA is a major component of the human genome, and includes loci contributing to human disease. Minisatellites include the most variable human loci described to date, and the mechanisms by which this variation is generated in humans have been studied in detail. Integration of human minisatellites into yeast not only provides a model for further dissecting the molecular basis of length change...
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