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Article

Chemically induced changes in the spectrum of amplifications of the human minisatellite MS1 integrated in chromosome III of a haploid yeast strain.

Molecular & general genetics : MGG - 1 Jan 1994

Agurell E, Cederberg H, Hedenskog M, Rannug U

Abstract excerpt

To study chemically induced DNA amplifications we used the haploid Saccharomyces cerevisiae strain TR(MS1)-1 carrying an integrated chromosomal copy of the human minisatellite. MS1. Chemicals with different mechanisms of action were tested in this strain: methyl methanesulphonate, ethylene oxide (EO), propylene oxide (PO), camptothecin, 2,3,7,8-tetrachlorodibenso-p-dioxin (TCDD) and reserpine. No increase in...

Topics

Alleles
Camptothecin
Chromosomes, Fungal
DNA, Satellite
Dimethyl Sulfoxide
Epoxy Compounds
Ethylene Oxide
Gene Amplification
Haploidy
Humans
Methyl Methanesulfonate

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Polychlorinated Dibenzodioxins

Repetitive Sequences, Nucleic Acid

Reserpine

Saccharomyces cerevisiae

Source

Identifiers

PMID: 8159163
DOI: 10.1007/BF00391006

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 29 Aug 2026. Prepared record publication-8159163-2026-08-29.1. Manifest publication-graph-cohort-2026-08-29.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 29 Aug 2026.

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