Mutations affecting growth cone guidance in Drosophila: genes necessary for guidance toward or away from the midline.

Abstract excerpt

We performed a large-scale screen for mutations that affect the development of CNS axon pathways in the Drosophila embryo. We screened embryos from over 13,500 balanced lines and saved over 250 mutant lines whose phenotypes suggest possible defects in growth cone guidance. Here we focus on two ne...

Topics

• Animals
• Axons
• Central Nervous System
• Drosophila
• Genes, Insect
• Mutation
• Neural Pathways
• Phenotype