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Article

Slit/Robo-mediated axon guidance in Tribolium and Drosophila: divergent genetic programs build insect nervous systems.

Developmental biology - 1 Mar 2012

Evans Timothy A, Bashaw Greg J

Abstract excerpt

As the complexity of animal nervous systems has increased during evolution, developmental control of neuronal connectivity has become increasingly refined. How has functional diversification within related axon guidance molecules contributed to the evolution of nervous systems? To address this question, we explore the evolution of functional diversity within the Roundabout (Robo) family of axon guidance...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

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Identifiers

PMID: 22245052
DOI: 10.1016/j.ydbio.2011.12.046
PMCID: PMC4128232

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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Slit/Robo-mediated axon guidance in Tribolium and Drosophila: divergent genetic programs build insect nervous systems.PMID 22245052Read ↗

Short-range and long-range guidance by slit and its Robo receptors. Robo and Robo2 play distinct roles in midline guidance.Semantic proximity Read ↗

Short-range and long-range guidance by Slit and its Robo receptors: a combinatorial code of Robo receptors controls lateral position.Semantic proximity Read ↗

Mutations affecting growth cone guidance in Drosophila: genes necessary for guidance toward or away from the midline.Semantic proximity Read ↗

Crossing the midline: roles and regulation of Robo receptors.Semantic proximity Read ↗

Slit is the midline repellent for the robo receptor in Drosophila.Semantic proximity Read ↗

Attractive and repulsive functions of Slit are mediated by different receptors in the Drosophila trachea.Semantic proximity Read ↗

Robo1 and Robo2 cooperate to control the guidance of major axonal tracts in the mammalian forebrain.Semantic proximity Read ↗

Projections of Drosophila multidendritic neurons in the central nervous system: links with peripheral dendrite morphology.Semantic proximity Read ↗

Alternative splicing of the Robo3 axon guidance receptor governs the midline switch from attraction to repulsion.Semantic proximity Read ↗

RETRACTED: Hierarchical organization of guidance receptors: silencing of netrin attraction by slit through a Robo/DCC receptor complex.Semantic proximity Read ↗

Genetic specification of axonal arbors: atonal regulates robo3 to position terminal branches in the Drosophila nervous system.Semantic proximity Read ↗

ROBO directs axon crossing of segmental boundaries by suppressing responsiveness to relocalized Netrin.Semantic proximity Read ↗

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