Article
The midline of the Drosophila central nervous system: a model for the genetic analysis of cell fate, cell migration, and growth cone guidance.
Cell - 22 Feb 1991
Klämbt C, Jacobs J R, Goodman C S
Abstract excerpt
A row of mesectodermal cells separates the two lateral neurogenic regions in the Drosophila embryo and generates a discrete set of glia and neurons. Most CNS growth cones initially head straight toward the midline, suggesting that these midline cells play a key role in the formation of the axon commissures. We have used antibodies that stain the first axons, beta-galactosidase enhancer trap lines that selectively...
Topics
- Animals
- Axons
- Cell Movement
- Drosophila
- Ectoderm
- Embryo, Nonmammalian
- Mesoderm
- Microscopy, Electron
- Mutation
- Nervous System
- Nervous System Physiological Phenomena