Article
[Hereditary predisposition for cancer of the breast and the ovary].
Bulletin du cancer - 1 Oct 1993
Lalle P, Stoppa-Lyonnet D, Mazoyer S, Rio P, Girodet C, Hardouin A, Narod S A, Sobol H, Bignon Y J
Abstract excerpt
Familial breast cancers represent about 10% of all cases of breast cancers. A predisposition locus has been located in the 17q21 chromosomal region. Nineteen French breast and breast-ovarian cancer families were tested for linkage with five highly polymorphic 17q markers. The five breast-ovarian cancer families as a group give positive evidence for linkage, whereas the 14 breast cancer families do not....
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