Genetic linkage analysis in familial breast and ovarian cancer: results from 214 families. The Breast Cancer Linkage Consortium.

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Article

Genetic linkage analysis in familial breast and ovarian cancer: results from 214 families. The Breast Cancer Linkage Consortium.

American journal of human genetics - 1 Apr 1993

Easton D F, Bishop D T, Ford D, Crockford G P

Abstract excerpt

Breast cancer is known to have an inherited component, consistent in some families with autosomal dominant inheritance; in such families the disease often occurs in association with ovarian cancer. Previous genetic linkage studies have established that in some such families disease occurrence is...

Topics

Adult
Aged
Aged, 80 and over
Alleles
Base Sequence
Breast Neoplasms
Chromosome Mapping
Chromosomes, Human, Pair 17
DNA Probes
DNA, Neoplasm
Family Health
Female
Gene Expression
Gene Expression Regulation, Neoplastic
Genetic Linkage
Genetic Markers
Genetic Predisposition to Disease
Genetic Variation

Source

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Identifiers

PMID: 8460634
PMCID: PMC1682082

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 30 Aug 2026. Prepared record publication-8460634-2026-08-30.1. Manifest publication-graph-cohort-2026-08-30.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 30 Aug 2026.

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