Linkage analysis of 19 French breast cancer families, with five chromosome 17q markers.

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Article

Linkage analysis of 19 French breast cancer families, with five chromosome 17q markers.

American journal of human genetics - 1 Apr 1993

Mazoyer S, Lalle P, Narod S A, Bignon Y J, Courjal F, Jamot B, Dutrillaux B, Stoppa-Lyonnett D, Sobol H

Abstract excerpt

Nineteen French breast and breast-ovarian cancer families were tested for linkage with five chromosome 17q markers. The five breast-ovarian cancer families as a group give positive evidence for linkage, whereas the 14 breast cancer-only families do not. Heterogeneity of linkage of breast and breast-ovarian cancers is significant in France and supports the existence of more than one susceptibility gene.

Topics

Adult
Aged
Breast Neoplasms
Chi-Square Distribution
Chromosome Mapping
Chromosomes, Human, Pair 17
Family Health
Female
France
Genetic Linkage
Genetic Markers

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Genetic Predisposition to Disease

Genetic Variation

Humans

Lod Score

Male

Middle Aged

Neoplastic Syndromes, Hereditary

Source

Open in PubMed Open full text

Identifiers

PMID: 8096359
PMCID: PMC1682088

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 29 Aug 2026. Prepared record publication-8096359-2026-08-29.1. Manifest publication-graph-cohort-2026-08-29.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 29 Aug 2026.

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