Article
Linkage of a major breast cancer gene to chromosome 17q12-21: results from 15 Edinburgh families.
American journal of human genetics - 1 Apr 1993
Cohen B B, Porter D E, Wallace M R, Carothers A, Steel C M
Abstract excerpt
DNA from members of 15 pedigrees each containing between three and eight cases of breast cancer have been collected from southeastern Scotland. Polymorphic markers on chromosome 17q were screened to locate a putative breast cancer gene by using DNA from relevant individuals within these families. Pairwise LOD scores were calculated for markers D17S74, NM23, D17S588, and D17S579. The maximal summated LOD for the...
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