Article
Genome-wide linkage scan for breast cancer susceptibility loci in Swedish hereditary non-BRCA1/2 families: suggestive linkage to 10q23.32-q25.3.
Genes, chromosomes & cancer - 1 Mar 2007
Bergman Annika, Karlsson Per, Berggren Jonna, Martinsson Tommy, Björck Karin, Nilsson Staffan, Wahlström Jan, Wallgren Arne, Nordling Margareta
Abstract excerpt
The two breast cancer genes BRCA1 and BRCA2 were identified more than 10 years ago and, depending on population, mutations in these genes are responsible for a varying percentage of familial breast cancer. In more than half the families, the increased risk of breast cancer cannot be explained by mutations in these genes, and the goal of this study was to locate novel susceptibility genes. One of the main...
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