Familial male breast cancer is not linked to the BRCA1 locus on chromosome 17q.

doi:10.1038/ng0594-103

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Article

Familial male breast cancer is not linked to the BRCA1 locus on chromosome 17q.

Nature genetics - 1 May 1994

Stratton M R, Ford D, Neuhasen S, Seal S, Wooster R, Friedman L S, King M C, Egilsson V, Devilee P, McManus R

Abstract excerpt

Breast cancer in men is about a hundredfold less common than in women and this has hindered research into its genetic basis. We have examined 22 families with at least one case of male breast cancer for linkage to the hereditary breast and ovarian cancer locus, BRCA1, on chromosome 17q. We found...

Topics

Breast Neoplasms
Chromosomes, Human, Pair 17
Female
Genetic Markers
Genetic Predisposition to Disease
Humans
Lod Score
Male
Ovarian Neoplasms
Pedigree
Risk Factors
Sex Factors

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