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Article

Detection of Point Mutations in the Kirsten-ras Oncogene Provides Evidence for the Multicentricity of Pancreatic Carcinoma

1 Feb 1993

Abstract excerpt

It has been reported that multicentricity of pancreatic carcinomas extending beyond the pancreatic duct occur in 15% to 40% of patients. This has been difficult to confirm, however, with currently available histologic techniques. Mutations in the Kirsten (Ki)-ras oncogene, which can be detected frequently in pancreatic carcinomas using the polymerase chain reaction (PCR), may serve as a potential clonal marker of...

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PMID: 8439212
DOI: 10.1097/00000658-199302000-00007

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Related research

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Detection of Point Mutations in the Kirsten-ras Oncogene Provides Evidence for the Multicentricity of Pancreatic CarcinomaPMID 8439212Read ↗

Distinguishing pancreatic carcinoma from other periampullary carcinomas by analysis of mutations in the Kirsten-ras oncogene.Semantic proximity Read ↗

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Ras gene mutations in intraductal papillary neoplasms of the pancreas. Analysis in five cases.Semantic proximity Read ↗

Crude isolation of DNA from unselected human pancreatic tissue and amplification by the polymerase chain reaction of Ki-ras oncogene to detect point mutations in pancreatic cancer.Semantic proximity Read ↗

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