Article
K-ras mutation in focal proliferative lesions of human pancreas.
Cancer epidemiology, biomarkers & prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology - 1 Jun 1998
Terhune P G, Phifer D M, Tosteson T D, Longnecker D S
Abstract excerpt
The K-ras gene is mutated in > or =75% of human pancreatic adenocarcinomas and in a number of hyperplastic ductal lesions from noncarcinoma patients. In this study, the incidence of K-ras mutation was determined in a spectrum of focal proliferative pancreatic lesions to evaluate their preneoplast...
Topics
- Adenocarcinoma
- Biomarkers, Tumor
- DNA Primers
- Genes, ras
- Humans
- Immunohistochemistry
- Mutation
- Pancreatic Diseases
- Pancreatic Neoplasms
- Polymorphism, Restriction Fragment Length
- Predictive Value of Tests
