Article
Multiple K-ras mutations in hyperplasia and carcinoma in cases of human pancreatic carcinoma.
Japanese journal of cancer research : Gann - 1 Aug 1999
Matsubayashi H, Watanabe H, Yamaguchi T, Ajioka Y, Nishikura K, Iwafuchi M, Yamano M, Kijima H, Saito T
Abstract excerpt
Mucous cell hyperplasia (MCH) has been considered an important precursor of pancreatic ductal carcinoma based on histological and molecular research, although various K-ras mutations rates are seen among cases with pancreatic carcinoma, chronic pancreatitis and normal pancreas, with a wide range of histological characters. To investigate the premalignant potential of MCH and the multicentricity of pancreatic...
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