Ki-ras and p53 mutations in pancreatic ductal adenocarcinoma.

doi:10.1097/00006676-199601000-00002

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Article

Ki-ras and p53 mutations in pancreatic ductal adenocarcinoma.

Pancreas - 1 Jan 1996

Rall C J, Yan Y X, Graeme-Cook F, Beauchamp R, Yandell D W, Povoski S P, Rustgi A K

Abstract excerpt

Pancreatic adenocarcinoma involves activation of the Ki-ras oncogene, inactivation of the p53 tumor suppressor gene, and dysregulation of growth factors and perhaps metastasis genes. Ki-ras oncogene point mutations are known to be involved in pancreatic oncogenesis. The p53 tumor suppressor gene...

Topics

Adenocarcinoma
Adult
Aged
Exons
Female
Genes, ras
Humans
Male
Middle Aged
Mutation
Pancreatic Neoplasms
Tumor Suppressor Protein p53

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