Article
The E1B 19-kilodalton protein is not essential for transformation of rodent cells in vitro by adenovirus type 5.
Journal of virology - 1 Mar 1993
Telling G C, Williams J
Abstract excerpt
The newly constructed adenovirus type 5 mutant in1 carries a single AT base pair insertion immediately after nucleotide position 1715 in the E1B gene sequence which destroys the proximal AUG normally present in E1B messages and prevents production of intact E1B 19-kDa protein in infected cells. We have used in1, variants of in1 containing mutant alleles of viral genes known to enhance transformation frequency,...
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