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Article

Adenovirus E1B 19-kilodalton protein overcomes the cytotoxicity of E1A proteins.

Journal of virology - 1 Jun 1991

White E, Cipriani R, Sabbatini P, Denton A

Abstract excerpt

Infection with adenovirus mutants carrying either point mutations or deletions in the coding region for the 19-kDa E1B gene product (19K protein) causes degradation of host cell and viral DNAs (deg phenotype) and enhanced cytopathic effect (cyt phenotype). Therefore, one function of the E1B 19K protein is to protect nuclear DNA integrity and preserve cytoplasmic architecture during productive adenovirus...

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Identifiers

PMID: 1851867
DOI: 10.1128/JVI.65.6.2968-2978.1991
PMCID: PMC240940

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Source receipt: pubmed, retrieved 7 Sept 2026.

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Adenovirus E1B 19-kilodalton protein overcomes the cytotoxicity of E1A proteins.PMID 1851867Read ↗

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