Alterations in cellular phenotype induced by the type 5 adenovirus E1A and the beta 1 protein kinase C genes in cloned rat embryo fibroblast cells.

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Article

Alterations in cellular phenotype induced by the type 5 adenovirus E1A and the beta 1 protein kinase C genes in cloned rat embryo fibroblast cells.

Cellular and molecular biology - 1 Feb 1992

Su Z Z, O'Brian C A, Fisher P B

Abstract excerpt

The E1A gene of adenovirus type 5 (Ad5) induces morphological transformation and anchorage-independent growth in cloned rat embryo fibroblast (CREF) cells. In contrast, CREF cells transfected with a beta 1 protein kinase C (PKC) gene and expressing low-levels of beta 1 PKC display a CREF-like mor...

Topics

Adenoviridae
Adenovirus Early Proteins
Animals
Cell Division
Cell Line
Cell Transformation, Viral
Genes, Viral
Oncogene Proteins, Viral
Phenotype
Protein Kinase C
Rats
Tetradecanoylphorbol Acetate
Transfection

Source

Open in PubMed

Identifiers

PMID: 1532767

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 30 Aug 2026. Prepared record publication-1532767-2026-08-30.1. Manifest publication-graph-cohort-2026-08-30.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 30 Aug 2026.

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