Article
A role for immunoglobulin D: interference with tolerance induction.
European journal of immunology - 1 Jan 1993
Carsetti R, Köhler G, Lamers M C
Abstract excerpt
We have studied the induction and maintenance of tolerance in the B lymphocyte compartment. Neonatal and adult transgenic mice which expressed either surface IgM (sIgM) or sIgM and sIgD anti-2,4,6-trinitrophenyl (TNP) were treated with soluble mono- and multivalent forms of TNP-modified carriers. We compared the B cell compartment of mice treated with antigen and of littermates injected with phosphate-buffered...
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