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Article

The unique antigen receptor signaling phenotype of B-1 cells is influenced by locale but induced by antigen.

Journal of immunology (Baltimore, Md. : 1950) - 15 Aug 2002

Chumley Michael J, Dal Porto Joseph M, Cambier John C

Abstract excerpt

Normal animals contain an autoreactive B lymphocyte subset, the B-1 subset, which is controlled by undefined mechanisms to prevent autoimmunity. Using a V(H)11V(kappa)9 Ig transgenic mouse, with a specificity prototypic of the subset, we have explored conditions responsible for the previously reported Ag hyporesponsiveness of these cells. We report that peritoneal V(H)11V(kappa)9 B cells exhibit typical B-1...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

Identifiers

PMID: 12165494
DOI: 10.4049/jimmunol.169.4.1735

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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