Article
Differential expression of activation markers during tolerance induction by superantigens in T-cell receptor (beta-chain) transgenic mice.
Cellular immunology - 1 Jul 1994
Perkins D L, Listman J A, Wang Y, Ho S S, Finn P W, Rimm I J
Abstract excerpt
To investigate the process of tolerance induction we have developed an in vivo model using TCR beta-chain transgenic mice tolerized with the superantigen staphylococcal enterotoxin B. We have previously demonstrated that tolerized peripheral T cells were anergic when stimulated in vitro with immu...
Topics
- Animals
- Antibodies, Monoclonal
- Cell Count
- Enterotoxins
- Female
- Immune Tolerance
- Kinetics
- Lymph Nodes
- Lymphocyte Activation
- Male
- Mice
- Mice, Inbred C57BL
- Mice, Transgenic
- Phenotype
- Receptors, Antigen, T-Cell, alpha-beta
- Spleen
- Staphylococcus aureus
- Superantigens