Article
Expression of the retinoblastoma susceptibility gene in childhood rhabdomyosarcomas.
Journal of the National Cancer Institute - 20 Jan 1993
De Chiara A, T'Ang A, Triche T J
Abstract excerpt
BACKGROUND: Alveolar and embryonal rhabdomyosarcomas are soft-tissue tumors that occur mainly in childhood. The more aggressive alveolar subtype has been found to possess a characteristic chromosomal abnormality located near the retinoblastoma susceptibility gene (RB1). RB1 is a tumor suppressor...
Topics
- Breast Neoplasms
- Child
- Eye Neoplasms
- Female
- Fluorescent Antibody Technique
- Genes, Retinoblastoma
- Genetic Predisposition to Disease
- Humans
- Immunohistochemistry
- RNA, Messenger
- RNA, Neoplasm
- Retinoblastoma
- Retinoblastoma Protein
- Rhabdomyosarcoma
- Tumor Cells, Cultured
