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Article

Ubiquitous aberrant RASSF1A promoter methylation in childhood neoplasia.

Clinical cancer research : an official journal of the American Association for Cancer Research - 1 Feb 2004

Wong Ivy H N, Chan Jacqueline, Wong Joyce, Tam Paul K H

Abstract excerpt

PURPOSE AND EXPERIMENTAL DESIGN: The role of RASSF1A has been elucidated recently in regulating apoptosis and cell cycle progression by inhibiting cyclin D1 accumulation. Aberrant RASSF1A promoter methylation has been found frequently in multiple adult cancer types. Using methylation-specific PCR...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

Identifiers

PMID: 14871978
DOI: 10.1158/1078-0432.ccr-0378-3

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 2 Sept 2026. Prepared record publication-14871978-2026-09-02.2. Manifest publication-graph-cohort-2026-09-02.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 2 Sept 2026.

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