Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Altered expression and molecular abnormalities of cell-cycle-regulatory proteins in rhabdomyosarcoma.

Modern pathology : an official journal of the United States and Canadian Academy of Pathology, Inc - 1 Jun 2004

Takahashi Yukiko, Oda Yoshinao, Kawaguchi Ken-Ichi, Tamiya Sadafumi, Yamamoto Hidetaka, Suita Sachiyo, Tsuneyoshi Masazumi

Abstract excerpt

Rhabdomyosarcoma is the most commonly occurring soft-tissue sarcoma in children. Some reports have discussed the altered expression and molecular abnormalities of cell-cycle-regulatory proteins in rhabdomyosarcoma; however, variable frequencies of occurrence have been noted. In the current study, among 72 cases of rhabdomyosarcoma, the authors evaluated for the expression of p53, MDM2, p16, p21/WAF1, p27, cyclin...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Cyclin D1
Share to Cyclin-Dependent Kinase Inhibitor p27

Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

Share to Cyclin E

Share to E2F Transcription Factors

Share to E2F1 Transcription Factor

Share to Ki-67 Antigen

Share to Rhabdomyosarcoma

Share to Rhabdomyosarcoma, Embryonal

Source

Identifiers

PMID: 15098008
DOI: 10.1038/modpathol.3800101

Genes

MDM2

Variants

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence. Graph snapshot: 2026-09-29.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Altered expression and molecular abnormalities of cell-cycle-regulatory proteins in rhabdomyosarcoma.PMID 15098008Read ↗

Alterations of RB1 gene in embryonal and alveolar rhabdomyosarcoma: special reference to utility of pRB immunoreactivity in differential diagnosis of rhabdomyosarcoma subtype.Semantic proximity Read ↗

Molecular pathogenesis of rhabdomyosarcoma.Semantic proximity Read ↗

Epithelioid rhabdomyosarcoma: a clinicopathologic and molecular study.Semantic proximity Read ↗

Rhabdomyosarcomas in Adults and Children: An UpdateSemantic proximity Read ↗

Cytogenetic-clinicopathologic correlations in rhabdomyosarcoma: a report of five cases.Semantic proximity Read ↗

Clinicopathologic and survival correlates of embryonal rhabdomyosarcoma driven by RAS/RAF mutations.Semantic proximity Read ↗

Molecular profile of head and neck rhabdomyosarcomas: A systematic review and meta-analysis.Semantic proximity Read ↗

Diffuse Myogenin Expression by Immunohistochemistry is an Independent Marker of Poor Survival in Pediatric RhabdomyosarcomaSemantic proximity Read ↗

DNA repair systems in rhabdomyosarcoma.Semantic proximity Read ↗

RAS signaling dysregulation in human embryonal Rhabdomyosarcoma.Semantic proximity Read ↗

A novel and consistent amplicon at 13q31 associated with alveolar rhabdomyosarcomaSemantic proximity Read ↗

Association of ataxia telangiectasia mutated (ATM) gene mutation/deletion with rhabdomyosarcoma.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.