Article
Molecular analysis of neurovirulent strains of Sindbis virus that evolve during persistent infection of scid mice.
Journal of virology - 1 Nov 1993
Levine B, Griffin D E
Abstract excerpt
To understand the role of tissue-specific adaptation and antibody-induced selectional pressures in the evolution of neurovirulent viruses, we analyzed three strains of Sindbis virus isolated from the brains of persistently infected scid mice and four strains of Sindbis virus isolated from the brains of scid mice with viral reactivation following immune serum treatment. For each viral isolate, we tested...
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