Article
Atrial natriuretic factor and transgenic mice.
Hypertension (Dallas, Tex. : 1979) - 1 Oct 1993
Koh G Y, Klug M G, Field L J
Abstract excerpt
Atrial natriuretic factor (ANF) is a peptide hormone that induces potent but transient hypotensive and natriuretic responses on short-term administration. The role of the hormone in long-term cardiovascular regulation has remained elusive in part because of the temporal limitations of long-term infusion models and the extremely short half-life of the molecule in vivo. To circumvent these temporal limitations, a...
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