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Article

[Genetically engineered mice for study of human hypertension].

Nihon rinsho. Japanese journal of clinical medicine - 1 Aug 1997

Sugiyama F, Taniguchi K, Fukamizu A, Yagami K

Abstract excerpt

Human essential hypertension is generally recognized as a multifactorial disease based on genetic diathesis. Despite the usefulness of SHR and Dahl rats as laboratory tools, the genetic diathesis including the development of hypertension in these rats remains unclear. Rapid advances in embryonic engineering and molecular biological techniques may make it possible to develop transgenic mice and gene-targeted mice...

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PMID: 9284415

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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