[Genetically engineered mice for study of human hypertension].

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Article

[Genetically engineered mice for study of human hypertension].

Nihon rinsho. Japanese journal of clinical medicine - 1 Aug 1997

Sugiyama F, Taniguchi K, Fukamizu A, Yagami K

Abstract excerpt

Human essential hypertension is generally recognized as a multifactorial disease based on genetic diathesis. Despite the usefulness of SHR and Dahl rats as laboratory tools, the genetic diathesis including the development of hypertension in these rats remains unclear. Rapid advances in embryonic...

Topics

Animals
Atrial Natriuretic Factor
Disease Models, Animal
Humans
Hypertension
Kallikrein-Kinin System
Mice
Mice, Transgenic
Mutation
Nitric Oxide Synthase
Rats
Receptors, Adrenergic, alpha-2
Renin-Angiotensin System
Sodium-Hydrogen Exchangers

Source

Open in PubMed

Identifiers

PMID: 9284415

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 30 Aug 2026. Prepared record publication-9284415-2026-08-30.1. Manifest publication-graph-cohort-2026-08-30.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 30 Aug 2026.

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