[Functional role of angiotensin II predicted from the phenotypes of transgenic and knockout mice].

doi:10.1254/fpj.112.213

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Article

[Functional role of angiotensin II predicted from the phenotypes of transgenic and knockout mice].

Nihon yakurigaku zasshi. Folia pharmacologica Japonica - 1 Sept 1998

Fukamizu A

Abstract excerpt

The renin-angiotensin system, composed of enzymatic and signal-transduction cascades, plays a key role in the regulation of arterial blood pressure and in the development of certain forms of experimental and human hypertension. The products of this system, angiotensin peptides, exert a wide range...

Topics

Angiotensin II
Animals
Arteriosclerosis
Hypertension
Mice
Mice, Knockout
Mice, Transgenic
Phenotype
Renin-Angiotensin System

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