Article
[Functional role of angiotensin II predicted from the phenotypes of transgenic and knockout mice].
Nihon yakurigaku zasshi. Folia pharmacologica Japonica - 1 Sept 1998
Fukamizu A
Abstract excerpt
The renin-angiotensin system, composed of enzymatic and signal-transduction cascades, plays a key role in the regulation of arterial blood pressure and in the development of certain forms of experimental and human hypertension. The products of this system, angiotensin peptides, exert a wide range of physiologically important effects on many tissues, including those of the cardiovascular systems, through their...
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