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Article

Rearrangement and diversity of T cell receptor beta chain genes in thymocytes: a critical role for the beta chain in development.

Cell - 7 May 1993

Mallick C A, Dudley E C, Viney J L, Owen M J, Hayday A C

Abstract excerpt

Thymocytes from mice congenitally deficient for TCR alpha chain synthesis were examined for the status of their TCR beta chain genes, by DNA sequencing and by a novel technique that analyzes populations of gene rearrangements. TCR beta chain genes were predominantly productively rearranged, in contrast with the statistical prediction for a quasi-random rearrangement process. Therefore, productive TCR beta chain...

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Identifiers

PMID: 8387894
DOI: 10.1016/0092-8674(93)90138-g

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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