Article
Diversity and structure of genes of the alpha family of mouse T-cell antigen receptor.
Nature - 1 Jan 2000
Arden B, Klotz J L, Siu G, Hood L E
Abstract excerpt
We have analysed 19 complementary DNA clones encoding the alpha-chain of the T-cell antigen receptor derived from thymic transcripts, and find that 15 of them contain partial or complete variable (V alpha) genes. Seven of these genes cross-hybridize to over 40 germline V alpha gene segments in Southern blot analyses. Of the 19 joining (J alpha) sequences examined, 18 seem to be encoded by distinct gene segments,...
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