Diversity and structure of genes of the alpha family of mouse T-cell antigen receptor.

doi:10.1038/316783a0

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Article

Diversity and structure of genes of the alpha family of mouse T-cell antigen receptor.

Nature - 1 Jan 2000

Arden B, Klotz J L, Siu G, Hood L E

Abstract excerpt

We have analysed 19 complementary DNA clones encoding the alpha-chain of the T-cell antigen receptor derived from thymic transcripts, and find that 15 of them contain partial or complete variable (V alpha) genes. Seven of these genes cross-hybridize to over 40 germline V alpha gene segments in So...

Topics

Animals
Base Sequence
Cloning, Molecular
DNA
Genes
Genetic Variation
Immunoglobulin Variable Region
Macromolecular Substances
Mice
Nucleic Acid Conformation
Nucleic Acid Hybridization
Receptors, Antigen, T-Cell
Transcription, Genetic

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