Characterization of TCR Gene Rearrangements During Adult Murine T Cell Development

doi:10.4049/jimmunol.162.5.2575

Article

Characterization of TCR Gene Rearrangements During Adult Murine T Cell Development

1 Mar 1999

Abstract excerpt

Development of the alphabeta and gammadelta T cell lineages is dependent upon the rearrangement and expression of the TCRalpha and beta or gamma and delta genes, respectively. Although the timing and sequence of rearrangements of the TCRalpha and TCRbeta loci in adult murine thymic precursors has been characterized, no similar information is available for the TCRgamma and TCRdelta loci. In this report, we show...

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