Article
Junctional sequences of fetal T cell receptor beta chains have few N regions.
The Journal of experimental medicine - 1 Jul 1991
Feeney A J
Abstract excerpt
T cell receptors (TCRs) and immunoglobulins (Igs) derive a large fraction of their repertoire from diversity generated at the junctions of the V, D, and J coding segments. This diversity is derived both from the random deletion of nucleotides from the ends of coding regions and from the subsequen...
Topics
- Animals
- Animals, Newborn
- Base Sequence
- Chromosome Deletion
- DNA
- Fetus
- Genes, Immunoglobulin
- Genetic Variation
- Macromolecular Substances
- Mice
- Mice, Inbred BALB C
- Molecular Sequence Data
- Oligonucleotide Probes
- Polymerase Chain Reaction
- RNA
- Receptors, Antigen, T-Cell
- T-Lymphocytes
- Thymus Gland