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Article

The V beta 17+ T cell repertoire: skewed J beta usage after thymic selection; dissimilar CDR3s in CD4+ versus CD8+ cells.

The Journal of experimental medicine - 1 Nov 1991

Candéias S, Waltzinger C, Benoist C, Mathis D

Abstract excerpt

To ascertain how the actual repertoire of T cell receptors (TCRs) deviates from the theoretical, we have generated a large number of junctional region sequences from TCRs carrying the V beta 17 variable region. The greater than 600 sequences analyzed represent transcripts from nine different cell populations, permitting several comparisons: transcripts from an expressed vs. a non-expressed V beta 17 allele, those...

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Identifiers

PMID: 1940807
DOI: 10.1084/jem.174.5.989
PMCID: PMC2119013

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