Article
The V beta 17+ T cell repertoire: skewed J beta usage after thymic selection; dissimilar CDR3s in CD4+ versus CD8+ cells.
The Journal of experimental medicine - 1 Nov 1991
Candéias S, Waltzinger C, Benoist C, Mathis D
Abstract excerpt
To ascertain how the actual repertoire of T cell receptors (TCRs) deviates from the theoretical, we have generated a large number of junctional region sequences from TCRs carrying the V beta 17 variable region. The greater than 600 sequences analyzed represent transcripts from nine different cell...
Topics
- Alleles
- Amino Acid Sequence
- Animals
- Base Sequence
- CD4 Antigens
- CD8 Antigens
- Immunoglobulin Variable Region
- Mice
- Mice, Inbred C57BL
- Molecular Sequence Data
- Polymerase Chain Reaction
- Receptors, Antigen, T-Cell
- T-Lymphocytes
- Thymus Gland