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Article

Characterization of a second hamster lung fibroblast mutant with defects in phosphatidylinositol-specific phospholipase C.

The Journal of biological chemistry - 5 May 1993

Leonis M A, Silbert D F

Abstract excerpt

We report here further characterization of the Chinese hamster lung fibroblast mutant D1-9b displaying elevated agonist-induced phosphatidylinositol (PI) turnover responses relative to CCL39, the parental cell line (Rath, H. M., Doyle, G. A. R., and Silbert, D. F. (1989) J. Biol. Chem. 264, 13387-13390). These differences in PI turnover responses are further enhanced by long term (24 h) pretreatment of cells with...

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PMID: 8387494

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