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Article

Characterization of the differential roles of the twin C1a and C1b domains of protein kinase C-delta.

The Journal of biological chemistry - 9 Jan 2009

Pu Yongmei, Garfield Susan H, Kedei Noemi, Blumberg Peter M

Abstract excerpt

Classic and novel protein kinase C (PKC) isozymes contain two zinc finger motifs, designated "C1a" and "C1b" domains, which constitute the recognition modules for the second messenger diacylglycerol (DAG) or the phorbol esters. However, the individual contributions of these tandem C1 domains to PKC function and, reciprocally, the influence of protein context on their function remain uncertain. In the present...

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Identifiers

PMID: 19001377
DOI: 10.1074/jbc.M804796200
PMCID: PMC2613622

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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